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Rifampicin

CAS No. : 13292-46-1

MCE 国际站：Rifampicin

产品活性：Rifampicin 是一种有效的广谱抗生素，可抵抗细菌病原体。Rifampicin 具有抗流感病毒活性。Rifampicin 具有抗正痘活性。

研究领域：Anti-infection

作用靶点：Bacterial  |  Influenza Virus  |  Antibiotic  |  Orthopoxvirus

In Vitro: Rifampicin (100 microg/mL) can block the functional activity of P-glycoprotein. Rifampicin is not a substract for P-glycoprotein. The mechanism of rifampicin resistance is unassociated with the functional activity of P-glycoprotein.

In Vivo: Rifampicin (200, 400 mg/kg) can induce fatty liver at high concentration. Rifampicin (30 mg/kg, i.p.) treatment of S464P biofilms in vivo results in a slight decline, but earlier rebinds in bioluminescence from these catheters compared with the parental signal, whereas rifampicin has no affect on bioluminescence in mice infected with mutant H481Y.

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