XRCC6 monoclonal antibody, clone 529
产品名称： XRCC6 monoclonal antibody, clone 529
英文名称： XRCC6 monoclonal antibody, clone 529
产品编号： MAB8010
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant XRCC6.
- Immunogen:
- Recombinant protein corresponding to N-terminus of human XRCC6.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG
- Storage Buffer:
- In PBS, pH 7.2
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
The optimal working dilution should be determined by the end user.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 2547
- Gene Name:
- XRCC6
- Gene Alias:
- CTC75,CTCBF,G22P1,KU70,ML8,TLAA
- Gene Description:
- X-ray repair complementing defective repair in Chinese hamster cells 6
- Omim ID:
- 152690
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq
- Other Designations:
- ATP-dependent DNA helicase II, 70 kDa subunit,CTC box binding factor 75 kDa subunit,Ku autoantigen p70 subunit,Ku autoantigen, 70kDa,OTTHUMP00000028581,thyroid autoantigen 70kD (Ku antigen),thyroid autoantigen 70kDa (Ku antigen),thyroid-lupus autoantigen
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Central Nervous System Neoplasms
- Diabetes Mellitus, Type 2
- DNA Damage
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Genomic Instability
- Glioma
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Lung Neoplasms
- Male Urogenital Diseases