LMNA purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： LMNA purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： LMNA purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00004000-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human LMNA protein.
- Immunogen:
- LMNA (NP_733821.1, 1 a.a. ~ 664 a.a) full-length human protein.
- Sequence:
- METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of LMNA expression in transfected 293T cell line (H00004000-T02) by LMNA MaxPab polyclonal antibody.
Lane 1: LMNA transfected lysate(74.10 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 4000
- GeneBank Accession#:
- NM_170707.1
- Protein Accession#:
- NP_733821.1
- Gene Name:
- LMNA
- Gene Alias:
- CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,HGPS,IDC,LDP1,LFP,LGMD1B,LMN1,LMNC,PRO1
- Gene Description:
- lamin A/C
- Omim ID:
- 115200, 150330, 151660, 159001, 176670, 181350, 248370, 275210, 277700, 604929, 605588, 607920, 608056
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq
- Other Designations:
- 70 kDa lamin,OTTHUMP00000015843,OTTHUMP00000015848
- Related Disease
- Aging, Premature
- Alzheimer Disease
- Alzheimer disease
- Arrhythmia
- Atherosclerosis
- Atherosclerosis
- Atrial Fibrillation
- Calcinosis
- Cardiomyopathy, Dilated
- Cardiovascular Diseases
- Cerebrovascular Disorders
- Charcot-Marie-Tooth Disease
- Cognition
- Cognition Disorders
- Coronary Artery Disease
- Death, Sudden
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Edema