AGER monoclonal antibody, clone 1C5
产品名称： AGER monoclonal antibody, clone 1C5
英文名称： AGER monoclonal antibody, clone 1C5
产品编号： MAB1724
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant AGER.
- Immunogen:
- Recombinant protein corresponding to human AGER.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS (0.1% proclin, 2.0% Block Ace)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Western Blot (0.1 ug/mL)
Immunocytochemistry (1 ug/mL)
ELISA (0.1 ug/mL)
Flow Cyt (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- RAGE and soluble RAGE: potential therapeutic targets for cardiovascular diseases.
Koyama H, Yamamoto H, Nishizawa Y.Mol Med. 2007 Nov-Dec;13(11-12):625-35.
- 2.
- The amphoterin (HMGB1)/receptor for advanced glycation end products (RAGE) pair modulates myoblast proliferation, apoptosis, adhesiveness, migration, and invasiveness. Functional inactivation of RAGE in L6 myoblasts results in tumor formation in vivo.
Riuzzi F, Sorci G, Donato R.J Biol Chem. 2006 Mar 24;281(12):8242-53. Epub 2006 Jan 9.
- 3.
- Acute lung injury as an adverse event of gefitinib.
Inomata S, Takahashi H, Nagata M, Yamada G, Shiratori M, Tanaka H, Satoh M, Saitoh T, Sato T, Abe S.Anticancer Drugs. 2004 Jun;15(5):461-7.
- 4.
- Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury.
Yonekura H, Yamamoto Y, Sakurai S, Petrova RG, Abedin MJ, Li H, Yasui K, Takeuchi M, Makita Z, Takasawa S, Okamoto H, Watanabe T, Yamamoto H.Biochem J. 2003 Mar 15;370(Pt 3):1097-109.
- 5.
- Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases.
Taguchi A, Blood DC, del Toro G, Canet A, Lee DC, Qu W, Tanji N, Lu Y, Lalla E, Fu C, Hofmann MA, Kislinger T, Ingram M, Lu A, Tanaka H, Hori O, Ogawa S, Stern DM, Schmidt AM.Nature. 2000 May 18;405(6784):354-60.
- Entrez GeneID:
- 177
- Gene Name:
- AGER
- Gene Alias:
- MGC22357,RAGE
- Gene Description:
- advanced glycosylation end product-specific receptor
- Omim ID:
- 600214
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000029155,OTTHUMP00000029156,advanced glycosylation end product-specific receptor RAGE3,advanced glycosylation end product-specific receptor variant sRAGE1,advanced glycosylation end product-specific receptor variant sRAGE2,receptor for advanced
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Cerebral Amyloid Angiopathy
- Cognition
- Colitis, Ulcerative
- Coronary Artery Disease
- Crohn's disease
- Diabetes Complications
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetes, Gestational
- Diabetic Nephropathies
- Diabetic Retinopathy
- Edema