NAPA monoclonal antibody, clone 4E4
产品名称： NAPA monoclonal antibody, clone 4E4
英文名称： NAPA monoclonal antibody, clone 4E4
产品编号： MAB1807
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant NAPA.
- Immunogen:
- Recombinant protein corresponding to human NAPA.
- Host:
- Mouse
- Theoretical MW (kDa):
- 36
- Reactivity:
- Human
- Specificity:
- This antibody specifically recognizes alpha SNAP as a single band of ~36 KDa on western blot of rat kidney, rat brain and MDBK cells and do not recognize beta SNAP.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In 20 mM sodium phosphate buffer, 150 mM NaCl, pH 7.5 (50% glycerol)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Western Blot (0.5-5 ug/mL)
Immunoprecipitation (2-10 ug/mL)
The optimal working dilution should be determined by the end user.
- Application Image
- Western Blot
- Immunoprecipitation
- Entrez GeneID:
- 8775
- Gene Name:
- NAPA
- Gene Alias:
- SNAPA
- Gene Description:
- N-ethylmaleimide-sensitive factor attachment protein, alpha
- Omim ID:
- 603215
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. Platelets contain some of the same proteins, including NSF, p115/TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types. Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different. [provided by RefSeq
- Other Designations:
- alpha-SNAP