GRM2 polyclonal antibody
产品名称: GRM2 polyclonal antibody
英文名称: GRM2 polyclonal antibody
产品编号: PAB16412
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GRM2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to human GRM2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- N-terminal extracellular domain of human.
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 2912
- Protein Accession#:
- Q14416
- Gene Name:
- GRM2
- Gene Alias:
- GLUR2,GPRC1B,MGLUR2,mGlu2
- Gene Description:
- glutamate receptor, metabotropic 2
- Omim ID:
- 604099
- Gene Ontology:
- Hyperlink
- Gene Summary:
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- glutamate metabotropic receptor 2,glutamate receptor homolog
- Gene Pathway