RUNX2 (phospho S533) Peptide
产品名称: RUNX2 (phospho S533) Peptide
英文名称: RUNX2 (phospho S533) Peptide
产品编号: P1688
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of RUNX2.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to amino acids 450-480 at residues surrounding S465 of human RUNX2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells.
Rich JT, Rosova I, Nolta JA, Myckatyn TM, Sandell LJ, McAlinden A.Biochem Biophys Res Commun. 2008 Jul 18;372(1):230-5. Epub 2008 May 13.
- 2.
- Expression and function of Cbfa-1/Runx2 in thyroid papillary carcinoma cells.
Endo T, Ohta K, Kobayashi T.J Clin Endocrinol Metab. 2008 Jun;93(6):2409-12. Epub 2008 Apr 1.
- 3.
- Family-based association study of polymorphisms in the RUNX2 locus with hand bone length and hand BMD.
Ermakov S, Malkin I, Keter M, Kobyliansky E, Livshits G.Ann Hum Genet. 2008 Jul;72(Pt 4):510-8. Epub 2008 Mar 27.
- Entrez GeneID:
- 860
- Protein Accession#:
- NP_004339;Q13950
- Gene Name:
- RUNX2
- Gene Alias:
- AML3,CBFA1,CCD,CCD1,MGC120022,MGC120023,OSF2,PEA2aA,PEBP2A1,PEBP2A2,PEBP2aA,PEBP2aA1
- Gene Description:
- runt-related transcription factor 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq
- Other Designations:
- CBF-alpha 1,OTTHUMP00000016533,SL3-3 enhancer factor 1 alpha A subunit,SL3/AKV core-binding factor alpha A subunit,acute myeloid leukemia 3 protein,core-binding factor, runt domain, alpha subunit 1,osteoblast-specific transcription factor 2,polyomavirus e
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Bone Diseases
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Cleidocranial Dysplasia
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Fractures, Bone
- Genetic Predisposition to Disease
- Metabolic Syndrome X
- Neoplasms
- Ossification of Posterior Longitudinal Ligament
- Osteoporosis
- Tobacco Use Disorder