JAG1 monoclonal antibody (M07), clone 1B7
产品名称： JAG1 monoclonal antibody (M07), clone 1B7
英文名称： JAG1 monoclonal antibody (M07), clone 1B7
产品编号： H00000182-M07
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant JAG1.
- Immunogen:
- JAG1 (NP_000205, 905 a.a. ~ 1014 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- HKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHV
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.1 KDa) .
- MSDS:
Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 182
- GeneBank Accession#:
- NM_000214
- Protein Accession#:
- NP_000205
- Gene Name:
- JAG1
- Gene Alias:
- AGS,AHD,AWS,CD339,HJ1,JAGL1,MGC104644
- Gene Description:
- jagged 1 (Alagille syndrome)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq
- Other Designations:
- OTTHUMP00000030278,jagged 1
- Gene Pathway
- Related Disease
- Alagille Syndrome
- Alzheimer Disease
- Alzheimer disease
- Brain Diseases
- CADASIL
- Cardiovascular Diseases
- Cerebral Amyloid Angiopathy
- Chromosome Deletion
- Cleft Lip
- Cleft Palate
- Diabetes Mellitus, Type 2
- Down Syndrome
- Edema
- Fractures, Bone
- Genetic Predisposition to Disease
- Heart Defects, Congenital
- Hepatitis C
- Kidney Failure, Chronic
- Multiple Sclerosis