BMX (Human) Recombinant Protein
产品名称: BMX (Human) Recombinant Protein
英文名称: BMX (Human) Recombinant Protein
产品编号: P4216
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human BMX (P51813) full-length recombinant protein expressed in Sf9 cells.
- Theoretical MW (kDa):
- 110
- Form:
- Liquid
- Preparation Method:
- Insect cell (Sf9) expression system
- Purity:
- ≥ 80% by SDS-PAGE
- Activity:
- 29 nmol phosphate incorporated into Poly (Glu-Tyr) substrate per minute per mg protein at 30°C using a final concentration of 50 uM ATP (0.83 uCi/assay).
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM Dithiothreitol, 0.1 mM EGTA, 0.1 mM EDTA, 25% glycerol, 0.1 mM PMSF)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 1 ug/lane SDS-PAGE Stained with Coomassie Blue
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 660
- Protein Accession#:
- P51813
- Gene Name:
- BMX
- Gene Alias:
- ETK,PSCTK2,PSCTK3
- Gene Description:
- BMX non-receptor tyrosine kinase
- Omim ID:
- 300101
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified
- Other Designations:
- OTTHUMP00000022964,OTTHUMP00000022965,OTTHUMP00000022966
- Related Disease