FITC标记的AATK细胞凋亡关联酪氨酸激酶抗体
产品名称： FITC标记的AATK细胞凋亡关联酪氨酸激酶抗体
英文名称： Anti-AATK/FITC
产品编号： HZ-1510R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-AATK/FITC Conjugated antibody
| FITC标记的AATK细胞凋亡关联酪氨酸激酶抗体 |
| 英文名称 | Anti-AATK/FITC |
| 中文名称 | FITC标记的AATK细胞凋亡关联酪氨酸激酶抗体 |
| 别 名 | AATK; AATYK; AATYK1; Apoptosis associated tyrosine kinase; Apoptosis-associated tyrosine kinase; Brain apoptosis associated tyrosine kinase; Brain apoptosis-associated tyrosine kinase; CDK5 binding protein; CDK5-binding protein; KIAA0641; Lemur tyrosine kinase 1; LMR1; LMTK1; LMTK1_HUMAN; p35 binding protein; p35-binding protein; p35BP; Serine/threonine protein kinase LMTK1; Serine/threonine-protein kinase LMTK1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 151kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AATK |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] Function: Apoptosis associated tyrosine kinase May be involved in neuronal differentiation. Subunit: Interacts with CDK5. Subcellular Location: Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Tissue Specificity: Expressed in brain, and, to a lower extent, in kidney, heart, lung and skeletal muscle. Belongs to the protein kinase superfamily. Tyr protein kinase family. Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Contains 1 protein kinase domain. Database links: Entrez Gene: 9625 Human Omim: 605276 Human SwissProt: Q6ZMQ8 Human Unigene: 514575 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
该基因编码的蛋白在N端含有酪氨酸激酶结构域，在C端含有富含脯氨酸的结构域。该基因在凋亡过程中被诱导，并且该基因的表达可能是诱导髓系前体细胞生长停滞和/或凋亡的必要先决条件。该基因已被证明在神经母细胞瘤细胞系中产生神经元分化。发现了两个编码不同亚型的转录变体。[ RefSeq 2011军提供]