PMS2 MaxPab mouse polyclonal antibody (B01)
产品名称： PMS2 MaxPab mouse polyclonal antibody (B01)
英文名称： PMS2 MaxPab mouse polyclonal antibody (B01)
产品编号： H00005395-B01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human PMS2 protein.
- Immunogen:
- PMS2 (NP_000526, 1 a.a. ~ 862 a.a) full-length human protein.
- Sequence:
- MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- PMS2 MaxPab polyclonal antibody. Western Blot analysis of PMS2 expression in human spleen.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of PMS2 expression in transfected 293T cell line (H00005395-T01) by PMS2 MaxPab polyclonal antibody.
Lane 1: PMS2 transfected lysate(94.82 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of purified MaxPab antibody to PMS2 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 5395
- GeneBank Accession#:
- NM_000535
- Protein Accession#:
- NP_000526
- Gene Name:
- PMS2
- Gene Alias:
- HNPCC4,PMS2CL,PMSL2
- Gene Description:
- PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq
- Other Designations:
- DNA mismatch repair protein,H_DJ0042M02.9,PMS2 postmeiotic segregation increased 2,mismatch repair endonuclease,postmeiotic segregation increased 2
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Breast cancer
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Duodenal Neoplasms
- Endometrial Neoplasms
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Ileal Neoplasms
- Jejunal Neoplasms
- Kidney Failure, Chronic
- Lung Neoplasms
- Meningeal Neoplasms
- Meningioma
- Microsatellite Instability
- Neoplasm Invasiveness