Human Growth Factors & Cytokines
Recombinant Human IFN-λ 1





 





		Synonyms :
IL-29



		Description :
IFN λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are  distantly related to the IL-10 family and Interferons.  All three IFN-lambdas use a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14).  Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. (Kotenko, SV. et al. Nat Immunology 2003 [1] p. 69-77).  Recombinant human IFN-λ 1 is a 19.8 kDa protein containing 178 amino acid residues.



		Catalog #:
300-02L



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Recombinant human IFN-lambda 1 induces phosphorylation of STAT2.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
PTSKPTTTGK GCHIGRFKSL SPQELASFKK ARDALEESLK LKNWSCSSPV FPGNWDLRLL QVRERPVALE AELALTLKVL EAAAGPALED VLDQPLHTLH HILSQLQACI QPQPTAGPRP RGRLHHWLHR LQEAPKKESA GCLEASVTFN LFRLLTRDLK YVADGNLCLR TSTHPEST 



		PubMed Link :
IFN-lambda-1+OR+IL-29


Country of Origin :
USA
















        Size A
5μg
$80 
 


 



        Size B
20μg
$195 
 


 



        Size C
1mg
$3000 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.