FITC标记的血管内皮生长因子B抗体
产品名称： FITC标记的血管内皮生长因子B抗体
英文名称： Anti-VEGF-B/FITC
产品编号： HZ-1915R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-VEGF-B/FITC Conjugated antibody
FITC标记的血管内皮生长因子B抗体
| 英文名称 | Anti-VEGF-B/FITC |
| 中文名称 | FITC标记的血管内皮生长因子B抗体 |
| 别 名 | Vascuoar endothelial growth factor B; Vegfb; VEGF-B; VEGF B; VEGFB 167; Vrf; VEGF-related factor; VRF; VEGFB_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 生长因子和激素 激酶和磷酸酶 细胞膜受体 血管内皮细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 20kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VEGFB |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011] Function: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. Subunit: Homodimer; disulfide-linked. Can also form heterodimer with VEGF. Subcellular Location: Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. Post-translational modifications: VEGF-B186 is O-glycosylated. Similarity: Belongs to the PDGF/VEGF growth factor family. Database links: Entrez Gene: 7423 Human Entrez Gene: 22340 Mouse Entrez Gene: 89811 Rat Omim: 601398 Human SwissProt: P49765 Human SwissProt: P49766 Mouse SwissProt: O35485 Rat Unigene: 78781 Human Unigene: 15607 Mouse Unigene: 198550 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码PDGF（血小板衍生生长因子）/VEGF（血管内皮生长因子）家族的成员。VEGF家族成员调节血管的形成并参与内皮细胞生理学。该成员是VEGFR-1（血管内皮生长因子受体1）和NRP-1（神经素-1）的配体。小鼠的研究表明，该基因与核编码的线粒体基因共表达，编码的蛋白质特异性地控制脂肪酸的内皮摄取。另一种编码不同的异构体的剪接转录变体已被鉴定。[ RefSeq，SEP 2011提供]