GDF15 polyclonal antibody
产品名称： GDF15 polyclonal antibody
英文名称： GDF15 polyclonal antibody
产品编号： PAB6858
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of GDF15.
- Immunogen:
- A synthetic peptide corresponding to human GDF15.
- Sequence:
- C-QKTDTGVSLQTYDD
- Host:
- Goat
- Theoretical MW (kDa):
- 34.1
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:2000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells.
Wollmann W, Goodman ML, Bhat-Nakshatri P, Kishimoto H, Goulet RJ Jr, Mehrotra S, Morimiya A, Badve S, Nakshatri H.Carcinogenesis. 2005 May;26(5):900-7. Epub 2005 Jan 27.
- Applications
- Western Blot (Tissue lysate)
- GDF15 polyclonal antibody (Cat # PAB6858) (0.1 ug/mL) staining of human prostate lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 9518
- Protein Accession#:
- NP_004855.1
- Gene Name:
- GDF15
- Gene Alias:
- GDF-15,MIC-1,MIC1,NAG-1,PDF,PLAB,PTGFB
- Gene Description:
- growth differentiation factor 15
- Omim ID:
- 605312
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Bone morphogenetic proteins (e.g., BMP5; MIM 112265) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM
- Other Designations:
- NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1,PTGF-beta,prostate differentiation factor
- Related Disease
- Adenoma
- Adenomatous Polyps
- Alzheimer Disease
- Alzheimer disease
- Carcinoma
- Cardiovascular Diseases
- Colorectal Neoplasms
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Hypertrophy, Left Ventricular
- Lung Neoplasms
- Metabolic Syndrome X
- Neoplasm Metastasis
- Neoplasms
- Osteoporosis
- Prostate cancer