PTPRA (phospho S204) Peptide
产品名称： PTPRA (phospho S204) Peptide
英文名称： PTPRA (phospho S204) Peptide
产品编号： P1389
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of PTPRA.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S204 of human PTPRA.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Immunohistochemistry (1:50-100)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The protein tyrosine phosphatase alpha modifies insulin secretion in INS-1E cells.
Kapp K, Metzinger E, Kellerer M, Haring HU, Lammers R.Biochem Biophys Res Commun. 2003 Nov 14;311(2):361-4.
- 2.
- Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells.
Zhang XQ, Kondrikov D, Yuan TC, Lin FF, Hansen J, Lin MF.Oncogene. 2003 Oct 2;22(43):6704-16.
- 3.
- Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor.
Yahiro K, Wada A, Nakayama M, Kimura T, Ogushi K, Niidome T, Aoyagi H, Yoshino K, Yonezawa K, Moss J, Hirayama T.J Biol Chem. 2003 May 23;278(21):19183-9. Epub 2003 Mar 6.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with PTPRA (phospho S204) polyclonal antibody (Cat # PAB0577) which was peroxidase-conjugated to the secondary antibody followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 5786
- Protein Accession#:
- NP_002827;P18433-3
- Gene Name:
- PTPRA
- Gene Alias:
- HEPTP,HLPR,HPTPA,HPTPalpha,LRP,PTPA,PTPRL2,R-PTP-alpha,RPTPA
- Gene Description:
- protein tyrosine phosphatase, receptor type, A
- Omim ID:
- 176884
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq
- Other Designations:
- Leukocyte common antigen-related peptide (protein tyrosine phosphate),OTTHUMP00000030063,OTTHUMP00000030064,OTTHUMP00000030065,PTPLCA-related phosphatase,PTPase-alpha,protein tyrosine phosphatase, receptor type, alpha polypeptide,tyrosine phosphatase alph