ACSL5 polyclonal antibody
产品名称: ACSL5 polyclonal antibody
英文名称: ACSL5 polyclonal antibody
产品编号: PAB7030
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of ACSL5.
- Immunogen:
- A synthetic peptide corresponding to human ACSL5.
- Sequence:
- C-RTQIDSLYEHIQD
- Host:
- Goat
- Theoretical MW (kDa):
- 82.3, 76
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize isoform a (NP_057318.2) and isoform b (NP_976313.1 and NP_976314.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5.
Obermuller N, Keith M, Kopitz J, Autschbach F, Schirmacher P, Gassler N.Int J Colorectal Dis. 2006 Mar;21(2):130-4. Epub 2005 Apr 5.
- Entrez GeneID:
- 51703
- Protein Accession#:
- NP_057318.2;NP_976313.1;NP_976314.1
- Gene Name:
- ACSL5
- Gene Alias:
- ACS2,ACS5,FACL5
- Gene Description:
- acyl-CoA synthetase long-chain family member 5
- Omim ID:
- 605677
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- FACL5 for fatty acid coenzyme A ligase 5,OTTHUMP00000020489,OTTHUMP00000020490,fatty acid coenzyme A ligase 5,fatty-acid-Coenzyme A ligase, long-chain 5,long-chain acyl-CoA synthetase 5,long-chain fatty acid coenzyme A ligase 5