Anti-APC6抗体
产品名称： Anti-APC6抗体
英文名称： APC6
产品编号： YB--7832R
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
上海钰博生物科技有限公司
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Anti-APC6抗体
| 产品编号 | YB-7832R |
| 英文名称 | APC6 |
| 中文名称 | 细胞分裂周期蛋白16抗体 |
| 别 名 | ANAPC6; Anaphase promoting complex subunit 6; Anaphase-promoting complex subunit 6; Apc 6; CDC 16; CDC16 (cell division cycle 16 S. cerevisiae homolog); CDC16; CDC16 homolog; CDC16 protein; CDC16_HUMAN; CDC16Hs; Cell division cycle 16 homolog; Cell division cycle protein 16 homolog; CUT9; Cyclosome subunit 6. |
| 规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 细胞周期蛋白 细胞分化 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 72kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human APC6/CDC16:301-400/620 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Subunit: The APC/C is composed of at least 12 subunits. Interacts with PPP5C and CDC20. Subcellular Location: Cytoplasm; cytoskeleton; centrosome. Cytoplasm; cytoskeleton; spindle. Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle. Post-translational modifications: Phosphorylated. Phosphorylation on Ser-560 occurs specifically during mitosis. Similarity: Belongs to the APC6/CDC16 family. Contains 7 TPR repeats. SWISS: Q13042 Gene ID: 8881 Database links: Entrez Gene: 8881 Human Entrez Gene: 69957 Mouse Omim: 603461 Human SwissProt: Q13042 Human SwissProt: Q8R349 Mouse Unigene: 374127 Human Unigene: 182412 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |