RUNX2 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： RUNX2 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： RUNX2 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00000860-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human RUNX2 protein.
- Immunogen:
- RUNX2 (AAI60022.1, 1 a.a. ~ 507 a.a) full-length human protein.
- Sequence:
- MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of RUNX2 expression in transfected 293T cell line (H00000860-T01) by RUNX2 MaxPab polyclonal antibody.
Lane 1: RUNX2 transfected lysate(55.77 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 860
- GeneBank Accession#:
- BC160022.1
- Protein Accession#:
- AAI60022.1
- Gene Name:
- RUNX2
- Gene Alias:
- AML3,CBFA1,CCD,CCD1,MGC120022,MGC120023,OSF2,PEA2aA,PEBP2A1,PEBP2A2,PEBP2aA,PEBP2aA1
- Gene Description:
- runt-related transcription factor 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq
- Other Designations:
- CBF-alpha 1,OTTHUMP00000016533,SL3-3 enhancer factor 1 alpha A subunit,SL3/AKV core-binding factor alpha A subunit,acute myeloid leukemia 3 protein,core-binding factor, runt domain, alpha subunit 1,osteoblast-specific transcription factor 2,polyomavirus e
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Bone Diseases
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Cleidocranial Dysplasia
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Fractures, Bone
- Genetic Predisposition to Disease
- Metabolic Syndrome X
- Neoplasms
- Ossification of Posterior Longitudinal Ligament
- Osteoporosis
- Tobacco Use Disorder